Predictors of treatment outcomes in geriatric patients with odontoid fractures: AOSpine North America multi-centre prospective GOF study

Spine
Michael G FehlingsBranko Kopjar

Abstract

Multicenter prospective cohort study. To identify patient and treatment characteristics associated with treatment success or failure in the management of odontoid fractures. Odontoid fractures are the most common cervical spine fractures in the elderly and represent a significant management challenge with widely divergent views regarding operative versus nonoperative management. A total of 159 patients 65 years and older with radiographically confirmed type II odontoid fractures were enrolled at 10 sites in the United States and 1 site in Canada between January 2006 and May 2009. Subjects were followed at 6 and 12 months post-initial treatment with Neck Disability Index and SF-36v2 scores. Final treatment outcome was classified as failure or success. Treatment failure was defined as death by any cause, decline in Neck Disability Index by more than 9.5 absolute points, or occurrence of a major treatment-related complication. Baseline characteristics between the groups were compared using t test for the continuous variables and χ2 test for the categorical variables. Baseline characteristics associated with treatment outcomes were identified by multiple logistic stepwise regression analysis. A total of 101 (63.5%) patients were tr...Continue Reading

Associated Clinical Trials

References

Apr 1, 1979·Acta Orthopaedica Scandinavica·J S Jensen, E Tøndevold
Jan 1, 1978·Journal of Neurosurgery·M L ApuzzoT Kurze
Oct 1, 1995·The Journal of Bone and Joint Surgery. American Volume·J D ZuckermanV H Frankel
Jan 1, 1994·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·V PointillartJ Senegas
Jan 1, 1993·Journal of Neurosurgery·W C HaniganJ P Henderson
Aug 1, 1996·Journal of Spinal Disorders·K ChibaK Hirabayashi
Jun 1, 1996·Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention·Branko Kopjar
Nov 7, 1999·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·E J MüllerG Muhr
May 12, 2000·Spine·P J LennarsonB C Walters
Oct 5, 2001·Journal of Spinal Disorders·R C Sasso
Mar 3, 2005·The Journal of Bone and Joint Surgery. American Volume·C G MoranAndrew M Taylor
Jul 21, 2006·Journal of Neurosurgery. Spine·Eric M HornVolker K H Sonntag
Aug 10, 2007·The Journal of Spinal Cord Medicine·Mark J SokolowskiMargaret Szewczyk Sokolowski
Sep 21, 2007·Neurosurgery·Patrick PlatzerChristian Gaebler
Jan 16, 2008·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·S A MalikJ O'Byrne
Dec 19, 2008·Spine·Florentius KoechGregory M Malham
Jan 6, 2009·The Journal of Bone and Joint Surgery. American Volume·Joost J van MiddendorpF Cumhur Oner
Oct 15, 2010·Spine·James S HarropPaul A Anderson
Nov 19, 2011·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Robert W MolinariRyan W McAssey

Citations

May 20, 2014·Best Practice & Research. Clinical Rheumatology·Paul Gerdhem
Mar 12, 2016·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Christoph JostenUlrich J Spiegl
Oct 30, 2015·The Journal of the American Academy of Orthopaedic Surgeons·Theodore J ChomaDarrel Brodke
Sep 18, 2015·Neurosurgery·Gregory D SchroederAlexander R Vaccaro
Apr 1, 2014·BioMed Research International·Yohan RobinsonClaes Olerud
Jan 23, 2016·The Spine Journal : Official Journal of the North American Spine Society·Joseph E TanenbaumThomas E Mroz
Feb 15, 2015·The Spine Journal : Official Journal of the North American Spine Society·Ai-Min WuYong-Long Chi
Jul 4, 2016·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Said SadiqiF Cumhur Oner
Aug 20, 2016·Journal of Neurosurgery. Spine·Asdrubal Falavigna
Aug 20, 2016·Journal of Neurosurgery. Spine·Christopher S GraffeoMichelle J Clarke
Nov 5, 2016·World Neurosurgery·Asdrubal FalavignaK Daniel Riew
Jan 6, 2017·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Dominic GehweilerLukas Kamer
Aug 18, 2017·Journal of Orthopaedic Trauma·Scott C WagnerAlexander R Vaccaro
Feb 7, 2018·The Clinical Journal of Pain·Greg McIntoshHamilton Hall
Aug 8, 2019·JBJS Reviews·Vadim GozNicholas Spina
Oct 1, 2016·Current Reviews in Musculoskeletal Medicine·Megan E Gornet, Michael P Kelly
Jan 8, 2014·The Bone & Joint Journal·M VenkatesanJ R Braybrooke
Jul 12, 2016·Neurosurgery·Christopher S GraffeoMichelle J Clarke
Aug 5, 2017·Der Unfallchirurg·Matti ScholzPhilipp Kobbe
Apr 15, 2020·Geriatric Orthopaedic Surgery & Rehabilitation·Michael P CatalinoDeb A Bhowmick
Mar 25, 2018·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Axel FrankeErwin Kollig
Sep 3, 2020·Global Spine Journal·Michael P CatalinoDeb A Bhowmick
Feb 23, 2021·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Timothy LukinsRichard D Ferch
Jun 5, 2021·Surgical Neurology International·Brian FianiAlexander Rose

Related Concepts

Trending Feeds

Metabolic Syndrome & T2DM

Metabolic syndrome is a complex disorder characterized by a cluster of metabolic abnormalities including hypertension, obesity, type 2 diabetes, and dyslipidemia. Here is the latest research on metabolic syndrome and type 2 diabetes mellitus.

CRISPR Screens in Virology

This feed focuses on the application of CRISPR-Cas system in high-throughput genome-wide screens to identify genes that affect virus-host interactions. Here is the latest research.

Cryogenic Electron Microscopy

Cryogenic electron microscopy (Cryo-EM) allows the determination of biological macromolecules and their assemblies at a near-atomic resolution. Here is the latest research.

Crispr In Malaria

CRISPR-Cas system enables the editing of genes to create or correct mutations. This technology is being investigated to combat malaria by targeting specific stretches of vector DNA and editing the genome at precise locations. Here is the latest research.

RNA & Axonal Functions

This feed focuses on subcellular and translation regulation of RNA in Axons and how this influences Axonal Functions. Discover the latest research here.

CRISPR & Single Cell Analyses

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on CRISPR-Cas applications relevant to single cell analyses. Here is the latest research.

Olfactory Navigation

This feed focuses on the impact of smell and space perception, as well as mechanisms that underlie navigation behaviour in animals. Here is the latest research on olfactory navigation.

Riboswitches and Ribozymes

Ribozymes are catalytic RNAs that interact with a variety of small molecule substrates and cofactors, the intracellular abundance of which are sensed by riboswitches that modulate transcription, RNA stability, or translation. Here is the latest research.

Enzyme Evolution

This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.

Related Papers

The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease
L GuglielmettiE Concia
European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
P L HénauxX Morandi
European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Jeroen G J HuybregtsCarmen L A Vleggeert-Lankamp
© 2022 Meta ULC. All rights reserved