Cryogenic electron microscopy (Cryo-EM) allows the determination of biological macromolecules and their assemblies at a near-atomic resolution. Here is the latest research.
Bacterial protein structures can expedite the development of novel antibiotics. Here is the latest research on bacterial proteins and the resolution of their structures.
Bioenergetic processes, including cellular respiration and photosynthesis, concern the transformation of energy by cells. Here is the latest research on the role of calcium in bioenergetics.
Chaperones are proteins that play an essential role in protein folding, stability, assembly, and degradation. Their depletion or dysfunction has been implicated in protein folding disorders. Here is the latest research.
Cholesterol is essential for a variety of cellular processes, including cell growth and division, and it plays an important role in various signaling pathways. Here is the latest research on cholesterol synthesis and the role of cholesterol in cell signaling.
This feed focuses on endoplasmic reticulum biochemistry, and includes ER stress and the unfolded protein response.
Glycosylphosphatidylinositol (GPI) is a glycolipid anchor for several cell-surface proteins that play a role in various biological processes, including signal transduction, prion disease pathogenesis, and immune response. Here is the latest research.
Gangliosides are sialic acid-containing glycosphingolipids concentrated on cell surfaces and found in abundance in the nervous system. Gangliosides have several functions, including a role in cholesterol absorption. Here is the latest research.
This feed focuses on biological and bioinformatical technologies including high-throughput screening assays that that aim to identify metabolic proteins. Here is the latest research.
Imaging mass spectrometry enables the visualization and assessment of the spatial distribution of molecules, including biomarkers and metabolites, based on their molecular mass. Here is the latest research.
Intrinsically disordered proteins exhibit biological activity even though they lack a well-defined 3D structure in solution. Here is the latest research on their role in cells.